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CD59 抗体

This anti-CD59 antibody is a 兔 多克隆 antibody detecting CD59 in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6568850
发货至: 中国

Quick Overview for CD59 抗体 (ABIN6568850)

抗原

See all CD59 抗体
CD59

适用

  • 167
  • 15
  • 11
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 98
  • 92
  • 7
  • 6

克隆类型

  • 120
  • 80
  • 1
多克隆

标记

  • 84
  • 26
  • 15
  • 14
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD59 antibody is un-conjugated

应用范围

  • 114
  • 90
  • 67
  • 54
  • 47
  • 39
  • 27
  • 23
  • 16
  • 14
  • 13
  • 13
  • 11
  • 11
  • 9
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CD59

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CD59

    别名

    CD59

    背景

    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    分子量

    Observed_MW: 17kDa

    Calculated_MW: 14kDa

    基因ID

    966

    UniProt

    P13987

    途径

    Complement System
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